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However, it has unpleasant side effects and may eventually stop working. Cannabis products, including CBD oil, may help some people with Parkinson’s manage symptoms and reduce medication side effects. Research, however, has not proven that CBD oil works as a treatment method or that it is safe. People who want to try CBD should talk with a CBD-knowledgeable physician and start with a low dosage.

Dr Sagnik Bhattacharyya and Dr Latha Velayudhan at King's College London are testing whether CBD helps psychosis symptoms. They’re aiming to find out how safe the drug is, if it does have any side effects, the best way to administer the drug and the ideal dosage. The project is currently at stage 1, which will establish the safety of CBD and how much people should be taking.

The researchers need to recruit 24 people for this first stage. Once the researchers know whether CBD improves psychosis symptoms, the treatment would progress to a phase 2 clinical trial, on a much larger scale. Currently, there is no treatment for these symptoms that doesn’t have adverse effects. "Some people with Parkinson's have very distressing hallucinations and it can have a negative impact on their lives.

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People with PD are eager to find alternative methods to help their symptoms, leading many of these patients to look into whether other therapies, such as medical marijuana, also known as medical cannabis, can be useful. Previously, I wrote a blog on medical marijuana and PD which you may find interesting.

So today I’ll take a more in-depth look at CBD to help you better understand what it is and its possible use for symptoms of PD. (Of note, the acronym for CBD is confusing in the context of PD, since the acronym is also used to refer to cortico-basal degeneration, a neurodegenerative disease that shares some clinical properties with PD.

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Cannabidiol, or CBD, is one of the two main components of medical marijuana. (The other one is tetrahydrocannabinol or THC.) Pure CBD does not cause a “high” and does not pose a risk of abuse or dependence. THC on the other hand, can cause these effects. CBD has been studied extensively in the laboratory and has been shown to have anti-inflammatory and antioxidant properties.

Although this is interesting and potentially exciting information, there are numerous other chemicals that have been studied in the laboratory with these properties that did not result in clinical benefit when tried in humans. Therefore, clinical trials become essential to support any claims that CBD should be used for medical purposes.

There is a lot of confusion around this question, related to the fact that the law distinguishes between CBD extracted from hemp and CBD extracted from marijuana. In reality, hemp and marijuana are two different names for the cannabis plant, with hemp defined as cannabis containing less than 0. 3% THC.

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On the other hand, CBD derived from a cannabis plant containing more than 0. 3% THC is federally illegal – even if the CBD is purified and the product itself contains less than 0. 3% THC. To add to the confusion, is the fact that each state has its own laws that govern the use of CBD products which often contradict federal law.

These vary in: What the manufacturers state is in the product. That is, some formulations of CBD will state on their label that they also contain a small amount of THC or that they contain other cannabis-derived compounds, but not THC. Others state that they are pure CBD. The formulation.

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It is not just the Parkinson’s disease community that has taken an interest in CBD. There are countless health claims that CBD is helpful for a whole host of conditions. Clinical trial evidence to support the use of CBD however, is minimal. The only FDA-approved indication for CBD is to reduce seizure frequency in certain rare and severe forms of childhood epilepsy.

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(Three other cannabis related drug products that are not CBD, but rather synthetic THC, also have FDA approval and are used to treat loss of appetite and weight loss in patients with HIV, and severe nausea and vomiting due to chemotherapy). For all the other health claims, there is not enough clinical trial data to allow the FDA to state whether or not CBD is effective.

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This has not dimmed the enthusiasm of millions of CBD users for a wide range of medical conditions. Practically, CBD products can be obtained relatively easily at health food stores and online. They are not considered drugs (except for Epidiolex®), and therefore are not regulated by the Food and Drug Administration (FDA).