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There are very few human studies on CBD, and those that have been done include doses that are all over the map: In some studies, patients used 5 mg of CBD; in others, they took as much as 600 mg. To further add to the confusion, CBD comes in a number of forms — oils and tinctures, creams and lotions, pills, vaping, and edibles — and each one has differences in terms of bioavailability (the percent of active ingredient that gets into your bloodstream).

“Ultimately, it’s trial and error, but you have to go about it in a methodical way.” Here are some tips to guide you on how to find the right CBD dosage for your pain relief and other symptoms. Many factors, such as your body mass index (BMI), specific health condition(s) you have, medications you take, your health history, and the form of CBD you plan to use can influence how much CBD you may need to treat your symptoms.

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“I wouldn’t recommend starting CBD without the supervision of a physician,” says Dr. Patel, author of The CBD Solution. “Many times people purchase a CBD product, try a dose that that doesn’t work for them, switch products and spin their wheels. Or, worse, they develop side effects.” Ask your rheumatologist or primary care provider to recommend an expert, or find an expert near you by searching the directory of members of the Society of Cannabis Clinicians or the database maintained by your state’s medical marijuana program (if it has one).

Now what? The answer depends on which form of CBD you take. Figuring out how much CBD is in capsules or gummies is simple — just read the supplement facts section on the label. (If it says 10 mg of CBD per capsule, you’d take three capsules to get your 30 mg of CBD a day.) Oils and tinctures can be trickier because the packaging often states the amount of CBD in the entire bottle, not in a dropper.

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When it comes to CBD in topical form (creams, lotions, and salves), you’ll probably see the total amount of CBD in the container listed on the label. You’ll then have to divide that total by the number of millimeters in the package to determine how much is in each milliliter.

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You should then use a metric measuring spoon to scoop out 7.5 ml to get a 30 mg dose of CBD. No two patients respond to CBD in the same way. You and your doctor will probably need to adjust the dose either up or down until you hit the right balance of benefits without side effects.

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There’s a wide variety of factors that come into play,” says Dr. Patel. It can take a little while to get it right, so be patient. Many people do not see a difference in symptoms after one or two doses of CBD. It can take up to eight weeks of regular use to feel an impact, says Bridget Seritt, co-founder of the Canna-Patient Resource Connection, a Colorado-based organization that is working to protect patient rights and end stigma against those who choose cannabis as medicine.

“The most common side effects are fatigue and lethargy, and in rare cases diarrhea,” says Dr. Patel, who notes that CBD that’s taken topically less commonly causes side effects. Topical CBD is best used to address pain in a single joint, rather than widespread pain, she adds. No matter which form of CBD you use, pay attention to how you feel.

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While many people use cannabidiol to relieve pain, more scientific research is needed to be sure it is safe. Understanding cannabidiol can help overcome the stigma associated with it.Some people experience side effects when taking cannabidiol (CBD) and there are other factors to consider before using CBD oil for pain.In this article, we look at how CBD oil works and how people can use it to relieve chronic pain.More research is necessary to confirm that CBD is a safe option for relieving pain.CBD is one of more than 120 compounds called cannabinoids.Many plants contain cannabinoids, but people most commonly link them to cannabis.Unlike other cannabinoids — such as tetrahydrocannabinol (THC) — CBD does not produce a euphoric “high” or psychoactive effect.

It produces some cannabinoids of its own, which are called endocannabinoids. The ECS helps to regulate functions such as sleep, immune-system responses, and pain.When THC enters the body, it produces a “high” feeling by affecting the brain’s endocannabinoid receptors. This activates the brain’s reward system, producing pleasure chemicals such as dopamine.CBD is an entirely different compound from THC, and its effects are very complex.